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1.
Rev. bras. oftalmol ; 81: e0062, 2022. graf
Article in Portuguese | LILACS | ID: biblio-1407673

ABSTRACT

RESUMO Objetivo conhecer o perfil clínico e cirúrgico de pacientes que realizaram ceratoplastia em um hospital universitário. Métodos Trata-se de um estudo observacional analítico, do tipo transversal. Foram avaliadas as fichas de descrição cirúrgica dos prontuários dos pacientes transplantados nos anos de 2019 e 2020, a fim de analisar dados sociais e clínicos. Os dados foram tratados por meio do programa Microsoft Office Excel 2017. As variáveis numéricas foram analisadas com auxílio da estatística descritiva no programa Bioestat versão 5.3 (frequência, porcentagem, média). As informações descritivas foram analisadas qualitativamente. Resultados Foram realizados 167 procedimentos nesse período, notando-se faixa etária média de 45 anos, indivíduos do sexo masculino, receptores de tecidos doados no Pará ou provenientes do Estado do Ceará. Os transplantes foram majoritariamente ópticos, eletivos, com botão corneano doador em média de 8mm e receptor de 7,5mm. Quanto às indicações, a maioria era decorrente de distrofias corneanas, seguidas de leucoma e perfuração do globo ocular, com predominância da técnica cirúrgica penetrante, sutura interrompida e anestesia local. Conclusão O conhecimento desses dados é importante para considerar que o perfil clínico e cirúrgico dos pacientes do hospital estudado se aproxima da realidade nacional, sobretudo na indicação clínica.


ABSTRACT Objective to investigate the clinical and surgical profile of patients who performed keratoplasty in a university hospital. Methods It is a cross-sectional, observational study. The surgical description from the medical records of transplanted patients in the years 2019 and 2020 was assessed to analyze social and clinical data. Data were processed using the Microsoft Office Excel 2017 program. Numerical variables were analyzed using descriptive statistics in the Bioestat program version 5.3. Descriptive information was analyzed qualitatively. Results 167 procedures were performed in this period, with an average age of 45 years old, male individuals, recipients of tissue donated in Pará or sent from the State of Ceará. Transplants were mostly optic, elective, with an average corneal donor button of 8mm and recipient of 7.5mm. As for the indications, most were due to corneal dystrophies, followed by leukoma and perforation of the eyeball, with a predominance of the penetrating surgical technique, interrupted suture, and local anesthesia. Conclusion The knowledge of these data is important to consider that the clinical and surgical profile of patients in the hospital studied is close to the national reality, especially in clinical indication.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Tissue and Organ Procurement/statistics & numerical data , Corneal Transplantation/statistics & numerical data , Corneal Diseases/epidemiology , Health Profile , Cross-Sectional Studies , Observational Study , COVID-19 , Hospitals, University/statistics & numerical data
2.
Rev. bras. oftalmol ; 80(3): e0001, 2021. tab, graf
Article in Portuguese | LILACS | ID: biblio-1251331

ABSTRACT

RESUMO Objetivo: Descrever o perfil clínico, cirúrgico e geográfico de pacientes acompanhados em um hospital universitário e submetidos a transplante de tecido corneano penetrante, com descrição das indicações para o procedimento e do tempo médio na fila de espera. Métodos: Estudo transversal e retrospectivo, incluindo 40 olhos de 40 pacientes submetidos à ceratoplastia penetrante no período de 1° de janeiro de 2018 a 31 de dezembro de 2019, acompanhados em um hospital universitário em Alagoas. Os dados foram coletados por meio das fichas de informações cirúrgicas dos transplantes de córnea da Central de Notificação, Captação e Distribuição de Órgãos e Tecidos de Alagoas, adaptados aos objetivos da pesquisa. Resultados: Dos transplantes de córnea estudados, 52,5% (n=21) foram realizados em pacientes do sexo feminino, 62,5% (n=25) na faixa etária acima de 60 anos, com média de idade de 59,17 anos (±20,4). Todos ocorreram em pacientes que residiam no estado de Alagoas, sendo 60% deles na região intermediária de Maceió. As principais indicações para o transplante de córnea foram ceratopatia bolhosa do pseudofácico (n=11; 27,5%), descemetocele (n=9; 22,5%) e falência tardia do enxerto (n=6; 15%). Dentre os procedimentos, 70% foram realizados no olho esquerdo (n=28) e 65%(n=26) com propósito óptico; houve associação de extração de catarata em 22,5% (n=9), e 5% (n=2) apresentaram complicações peroperatórias. O tempo médio geral em lista de espera foi de 332,3 dias (11 meses), sendo 486 dias (2 anos e 4 meses) para cirurgias eletivas e 12,8 dias para as de urgência. Conclusão: O tempo de espera para cirurgias eletivas foi longo e inadequado. A principal condição indicadora para o transplante de córnea foi a ceratopatia bolhosa. O conhecimento do perfil dos transplantes de córnea pode permitir a identificação de grupos de risco para fins de prevenção e implementação de cuidados, que resultem em prognósticos mais favoráveis, bem como incentivar a implementação de políticas internas e externas para melhoria do sistema captação-doação.


ABSTRACT Objective: To describe the clinical, surgical, and geographic profile of patients submitted to corneal transplantation and followed up at a teaching hospital, and, with a description of the indications for the procedure and mean waiting time. Methods: A cross-sectional and retrospective study, including 40 eyes of 40 patients who underwent penetrating keratoplasty, from January 1, 2018 to December 31, 2019, followed up at a teaching hospital in Alagoas State. Data were collected using the surgical records of corneal transplants, from the Central Reporting, Procurement and Distribution of Organs and Tissues of Alagoas, and adjusted to the research objectives. Results: Of the corneal transplants studied, 52.5% (n=21) were performed in female patients; 62.5% (n=25) in the age group over 60 years; with a mean age of 59.17 years (± 20.4). All transplanted patients lived in the state of Alagoas, 60% of them in the intermediate metropolitan region of Maceió. The main indications for corneal transplantation were pseudophakic bullous keratopathy (27.5%, n=11), descemetocele (22.5%, n=9) and late graft failure (15%, n=6). Seventy percent (n= 28) of procedures were performed on the left eye and 65% (n=26) for optical purposes. There was an association of cataract extraction in 22.5% (n=9), and 5% (n=2) had perioperative complications. The mean waiting list time was 332.3 days (11 months); in that, 486 days (2 years and 4 months) for elective surgeries and 12.8 days for emergency surgeries. Conclusion: The waiting time for elective surgeries was long and inappropriate. The major indication for corneal transplantation was bullous keratopathy. Knowledge of the clinical profile of corneal transplants can enable identifying the risk groups for prevention and implementation of care, resulting in better prognosis, fostering implementation of internal and external policies to improve the procurement-donation system.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Corneal Transplantation/methods , Keratoplasty, Penetrating/methods , Corneal Diseases/epidemiology , Hospitals, University , Brazil , Epidemiology, Descriptive , Cross-Sectional Studies , Retrospective Studies
3.
Rev. Soc. Colomb. Oftalmol ; 53(1): 17-23, 2020. ilus., tab.
Article in Spanish | LILACS, COLNAL | ID: biblio-1128016

ABSTRACT

Introducción: Queratocono es un término clínico amplio, que describe un estado de la córnea derivado de su adelgazamiento focal y protrusión secundaria central, paracentral y/o periférica. Los reportes epidemiológicos globales revelan un amplio rango en cifras de prevalencia e incidencia que se podría explicar por las diferencias geográficas, factores de riesgo, tipo de población, métodos y criterios diagnósticos utilizados. En Colombia no hay estudios epidemiológicos que evalúen esta enfermedad de manera integral por lo que su frecuencia aún no ha podido ser determinada. Objetivo: identificar la prevalencia de Queratocono y Degeneración Marginal Pelucida (DMP) en el centro oftalmológico privado Clínica Barraquer, durante el periodo de tiempo comprendido entre enero de 2014 y enero de 2019. Diseño del estudio: estudio transversal de fuentes secundarias. Método: revisión de los registros médicos electrónicos de todos los pacientes que consultaron por primera vez; posteriormente, se filtraron por el diagnóstico de Ectasia Corneal y/o Queratocono. Cada una de las historias clínicas fue analizada por un oftalmólogo teniendo en cuenta los diagnósticos preestablecidos. Resultados: del grupo de 91.426 pacientes, 2.647 tenían Queratocono o DMP. Se estableció una prevalencia de Queratocono y DMP del 2.84%. La edad promedio al momento del diagnóstico fue de 29.7±12 años. El 42.8% eran mujeres y el 57.2% hombres. Conclusión: la ectasias corneales de tipo Queratocono y DMP, son enfermedades con una prevalencia significativa en la población colombiana evaluada en la clínica Barraquer; consideramos se requiere de programas de tamizaje visual para su detección y tratamiento oportunos.


Background: Keratoconus is a wide clinical term used to describe a corneal disease characterized by thinning and secondary central, paracentral or peripheral protrusion of the cornea. The global epidemiological reports reveal a wide range of prevalence and incidence, that may be explained by geographical differences, risk factors, kind of population, and methods and diagnostic criteria employed. There are no epidemiological studies to evaluate globally this disease in Colombia, therefore, its frequency has not been determined yet. Objective: to identify the prevalence of Keratoconus and Pellucid Marginal Degeneration (PMD) from January 2014 to January 2019 at the private ophthalmological center Clínica Barraquer. Study Design: cross-sectional study using secondary data. Method: a review of the electronic medical records of all patients who consulted for the first time was performed, and then, filtered by the initial diagnosis of Corneal Ectasia or Keratoconus. Each one of the medical records was analyzed by an ophthalmologist taking into account a series of pre-established diagnostic criteria. Results: of 91.426 patients, 2.647 had Keratoconus or PMD within the time interval of the study. A prevalence of 2.84% was determined in first time patients. The average age at the time of diagnosis was 29.7±12 years. 42.8% were female patients and 57.2% male patients. Conclusion: Keratoconus and PMD are diseases with significant prevalence in the Colombian population evaluated at the Barraquer clinic, thus, visual screening programs are required for accurate detection and treatment.


Subject(s)
Keratoconus/epidemiology , Epidemiologic Studies , Risk Factors , Cornea , Corneal Diseases/epidemiology , Eye Diseases
4.
Arq. bras. oftalmol ; 82(5): 377-380, Sept.-Oct. 2019. tab, graf
Article in English | LILACS | ID: biblio-1019430

ABSTRACT

ABSTRACT Purpose: To assess the frequency of corneal astigmatism before cataract surgery in a Brazilian sample. Methods: This clinic-based cross-sectional study was conducted at the Bonsucesso Federal Hospital, Rio de Janeiro, Brazil. Charts of patients who underwent cataract surgery over a two-year period were retrospectively reviewed, and preoperative keratometric measurements were collected and analyzed. Results: A total of 1707 eyes of 1045 patients were enrolled. The corneal astigmatism was less than 1.0 D in 971 eyes (56.9%), 1.0-1.99 D in 496 eyes (29.1%), 2.0-2.99 D in 157 eyes (9.2%), and more than 3.0 D in 83 eyes (4.9%). The mean corneal astigmatism was 0.92 ± (SD) 0.96 D (range 0 - 10.25 D). Conclusion: Over 40% of the patients undergoing cataract surgery enrolled in this study had more than 1.0 D of corneal astigmatism and may benefit from the use of toric intraocular lenses. These data can be useful for planning to make this technology available for patients.


RESUMO Objetivo: Avaliar a prevalência do astigmatismo corneano antes da cirurgia de catarata em pacientes brasileiros. Métodos: Este estudo transversal de base clínica foi realizado no Hospital Federal de Bonsucesso, Rio de Janeiro, Brasil. Os prontuários de pacientes submetidos à cirurgia de catarata durante um período de dois anos foram revisados retrospectivamente, e as medidas ceratométricas pré-operatórias foram coletadas e analisadas. Resultados: Um total de 1.707 olhos de 1045 pacientes foram incluídos. O astigmatismo corneano foi menor que 1,0 D em 971 olhos (56,9%), 1,0-1,99 D em 496 olhos (29,1%), 2,0-2,99 D em 157 olhos (9,2%) e mais de 3,0 D em 83 olhos (4,9%). A média do astigmatismo corneano foi de 0,92 ± (SD) 0,96 D (intervalo 0-10,25 D). Conclusão: Mais de 40% dos pacientes estudados submetidos à cirurgia de catarata incluídos neste estudo tinham mais de 1,0 D de astigmatismo corneano e podem se beneficiar do uso de lentes intraoculares tóricas. Esses dados podem ser úteis no planejar a disponibilização dessa tecnologia para os pacientes.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Astigmatism/epidemiology , Cataract/complications , Cataract Extraction , Corneal Diseases/epidemiology , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , Retrospective Studies , Cornea/physiopathology , Hospitals, Public
5.
Rev. Soc. Colomb. Oftalmol ; 52(1): 23-30, 2019. tab.
Article in Spanish | LILACS, COLNAL | ID: biblio-1026471

ABSTRACT

Introducción: La Iridociclitis Heterocrómica de Fuchs (IHF) es la causa del 2 a 7% de las uveítis anteriores, el astigmatismo corneal como condición de la IHF y como posible causa de la disminución de la visión, ha sido una entidad muy poco estudiada hasta el momento, tiene una gran importancia debido a que por la anisometropía que podría generar, puede llevar a alteraciones de la agudeza visual. Objetivo: Evaluar la existencia de astigmatismo corneal y/o aberraciones corneales inherentes a los ojos con Iridociclitis Heterocrómica de Fuchs. Diseño del estudio: Estudio transversal, analítico, de fuentes primarias. Método: Se realizó muestreo por conveniencia, en el cual se incluyeron 44 ojos de 22 pacientes con diagnóstico de IHF unilateral o bilateral. Para cada caso, se realizó tomografía corneal (Pentacam® AXL - OCULUS) y aberrometria (OPD-Scan III® - NIDEK) y se compararon ojos enfermos con los ojos sanos. Resultados: Se encontró una mediana de 1.35 (RIC: 0.50 ­ 1.70) para el astigmatismo de la cara anterior de los ojos enfermos .vs. 0.8 (RIC: 0.7 ­ 1.1) para el astigmatismo de la cara anterior de los ojos sanos (p= 0.135). Se identificó un astigmatismo en cara anterior >1.00 D en el 61.5% de los ojos enfermos .vs. 27.8% de los ojos sanos (p= 0.027) con un RR de 2.15. No se encontró una diferencia estadísticamente significativa entre los ojos enfermos y los ojos sanos para las aberraciones analizadas. Conclusión: El presente estudio no demuestra la existencia de astigmatismo o aberraciones inherentes a la IHF, pero evidencia una tendencia de mayor astigmatismo en los ojos con IHF, que posiblemente podría lograr significancia estadística con una muestra mayor.


Background: Fuchs heterochromic iridocyclitis (FHI) represents 2 to 7% of cases of anterior uveitis. To date, few studies have addressed corneal astigmatism as an inherent condition and as possible cause of decreased visual acuity in FHI patients. This may be relevant since the generated anisometropia may lead to alterations in visual acuity. Objective: To evaluate the presence of corneal astigmatism and/or corneal aberrations in patients with FHI. Study design: Analytic cross sectional study. Method: A convenient sampling was performed. The sample included 44 eyes of 22 patients with unilateral or bilateral FHI. All participants were studied by corneal tomography (Pentacam® AXL ­ OCULUS) and aberrometry (OPDScan III® - NIDEK); measurements of diseased and healthy eyes were compared. Results: Twenty-two patients were enrolled in this study. The mean age at diagnosis was 46.9 +/- 12 years, and 40.9% were men. FHI eyes exhibited a median astigmatism of the anterior surface of 1.35D (IQR: 0.50 ­ 1.70), compared to 0.8D (IQR: 0.7 ­ 1.1) observed in healthy eyes (p= 0.135). Anterior surface astigmatism >1.00 diopters (D) was found in 61.5% of diseased eyes compared to 27.8% of healthy eyes, with a risk ratio of 2.15. Regarding corneal aberrations, no statistically significant differences were identified between diseased and healthy eyes for the analyzed aberrations. Conclusion: While our current data does not show statistically signifi cant differences between groups that support that corneal astigmatism or aberrations are inherent to FHI-aff ected eyes, our study does show a trend that suggests increased presence of clinically relevant astigmatism in eyes with FHI. Statistical significance may be achieved with a larger sample size.


Subject(s)
Iridocyclitis , Astigmatism , Corneal Diseases/epidemiology , Corneal Wavefront Aberration
6.
Arq. bras. oftalmol ; 81(2): 116-119, Mar.-Apr. 2018. tab, graf
Article in English | LILACS | ID: biblio-950438

ABSTRACT

ABSTRACT Purpose: To determine the clinical characteristics and seasonal distribution of patients admitted to the ocular emergency department of a tertiary ophthalmology care center. Methods: The study cohort includes 27,120 patients who were admitted to ocular emergency room between November 2013 and November 2014. The age, sex, reason for admission, diagnosis, and complete ocular examination reports were recorded for each patient. X-ray and ultrasonographic examinations were performed if necessary. Results: The mean patient age was 32.83 ± 17.62 years (range, 0-95). The number of males was nearly two times the number of females, with 18,808 (69.4%) males and 8312 (30.6%) females. The diagnoses included viral conjunctivitis (7,859 patients; 29.0%), corneal foreign body (5,286 patients; 19.5%), bacterial conjunctivitis (3,892 patients; 14.4%), corneal abrasions (2,306 patients; 8.5%), and allergic conjunctivitis (1,433 patients; 5.3%) (Table 1). Other frequent diagnoses included subconjunctival hemorrhage, photo keratopathy, chemical eye injury, and penetrating and blunt eye injuries. Allergic conjunctivitis, ocular trauma, and corneal foreign body were more frequent in spring, whereas keratitis and chemical eye injury were more common in winter (chi-square test). The most common reasons for emergency room admission, in order of frequency, were viral conjunctivitis, corneal foreign body, bacterial conjunctivitis, and corneal abrasions. Conclusion: This study is the first long-term prospective study to evaluate the seasonal distribution and diagnosis of all adult and pediatric patients admitted to the emergency room for ocular conditions. The frequency of ophthalmological conditions seen in the emergency room may vary according to the season.


RESUMO Objetivo: Determinar as características clínicas e a distribuição sazonal dos pacientes admitidos no departamento de emergências oculares de um centro terciário de cuidados oftalmológicos. Métodos: Um total de 27.120 pacientes, admitidos no pronto atendimento ocular entre novembro de 2013 e novembro de 2014, foram incluídos neste estudo prospectivo. Idade, gênero, causa da admissão, diagnóstico e relatórios completos dos exames oculares dos pacientes foram registrados e exames de raios X e de ultrassonografia foram realizados quando necessários. Resultados: A idade média do paciente foi de 32,83 ± 17,62 anos (intervalo, 0-95). O número de homens era quase duas vezes maior que o número de mulheres, com 18.808 (69,4%) do sexo masculino e 8.312 (30,6%) do sexo feminino. Os diagnósticos incluíram conjuntivite viral (7.859 pacientes, 29,0%), corpo estranho corneano (5.286 pacientes, 19,5%), conjuntivite bacteriana (3.892 pacientes, 14,4%), abrasões corneanas (2.306 pacientes, 8,5%) e conjuntivite alérgica (1.433 pacientes, 5,3%) (Tabela 1). Outros diagnósticos freqüentes incluíram hemorragia subconjuntival, queratopatia fotográfica, lesões oculares químicas e lesões oculares penetrantes e contundentes. A conjuntivite alérgica, o trauma ocular e o corpo estranho da córnea foram mais frequentes na primavera, enquanto que a queratite e lesões oculares químicas foram mais comuns no inverno (teste qui-quadrado). Os motivos mais comuns para a admissão na sala de emergência, em ordem de frequência, foram conjuntivite viral, corpo estranho da córnea, conjuntivite bacteriana e abrasões da córnea. Conclusão: Este é o primeiro estudo prospectivo de longa duração avaliando as causas e a distribuição sazonal de todos os casos de admissão em um pronto atendimento oftalmológico para pacientes em idade adulta ou pediátrica. A frequência das causas de encaminhamento ao pronto atendimento pode variar em função da estação do ano.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Patient Admission/statistics & numerical data , Seasons , Eye Foreign Bodies/epidemiology , Conjunctivitis/epidemiology , Corneal Diseases/epidemiology , Emergency Service, Hospital/statistics & numerical data , Time Factors , Turkey/epidemiology , Prospective Studies , Sex Distribution
7.
Arq. bras. oftalmol ; 80(3): 168-171, May-June 2017. tab
Article in English | LILACS | ID: biblio-888104

ABSTRACT

ABSTRACT Purpose: The purpose of this study was to determine the indications and frequency of evisceration after penetrating keratoplasty (PK). Methods: The medical records of all patients who underwent evisceration after PK between January 1, 1995 and December 31, 2015 at Ankara Training and Research Hospital were reviewed. Patient demographics and the surgical indications for PK, diagnosis for evisceration, frequency of evisceration, and the length of time between PK and evisceration were recorded. Results: The frequency of evisceration was 0.95% (16 of 1684), and the mean age of the patients who underwent evisceration was 56.31 ± 14.82 years. The most common indication for PK that resulted in evisceration was keratoconus (37.5%), and the most common underlying cause leading to evisceration was endophthalmitis (56.25%). The interval between PK and evisceration ranged from 9 to 78 months. Conclusions: Although keratoplasty is one of the most successful types of surgery among tissue transplantations, our findings show that it is associated with a possible risk of evisceration.


RESUMO Objetivo: O objetivo deste estudo foi determinar as indicações e a frequência de evisceração ocular após cirurgia de ceratoplastia penetrante ou transplante de córnea (PK). Métodos: Foram analisados os registros médicos de todos os pacientes submetidos à evisceração após PK entre 1º de janeiro de 1995 e 31 de dezembro de 2015 no Hospital de Treinamento e Pesquisa de Ankara. Foram registradas a demografia do paciente e as indicações cirúrgicas de PK, diagnóstico de evisceração, frequência de evisceração, tempo entre PK e evisceração. Resultados: A frequência de evisceração foi de 0,95% (16 de 1684) e a média de idade foi de 56,31 ± 14,82 anos. A indicação mais comum para PK que terminou na evis ceração foi o ceratocone (37,5%) e a causa subjacente à evisceração foi a endoftalmite (56,25%). O intervalo entre PK e evisceração variou de 9 a 78 meses. Conclusão: Embora a ceratoplastia seja uma das cirurgias mais bem sucedidas entre os transplantes de tecidos, pode-se deduzir do estudo que não é tão inócua, pois pode evoluir para a evisceração ocular.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Young Adult , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Keratoplasty, Penetrating/adverse effects , Eye Evisceration/statistics & numerical data , Reoperation , Time Factors , Turkey/epidemiology , Medical Records , Endophthalmitis/surgery , Endophthalmitis/etiology , Endophthalmitis/epidemiology , Incidence , Retrospective Studies , Risk Factors , Treatment Outcome , Corneal Diseases/surgery , Corneal Diseases/etiology , Corneal Diseases/epidemiology
8.
Rev. latinoam. enferm. (Online) ; 25: e2897, 2017. tab, graf
Article in English | BDENF, LILACS | ID: biblio-845293

ABSTRACT

ABSTRACT Objective: clinically characterizing cornea transplant patients and their distribution according to indicated and post-operative conditions of cornea transplantation, as well as estimating the average waiting time. Method: a cross-sectional, descriptive and analytical study performed for all cornea transplants performed at a reference service (n=258). Data were analyzed using Statistical Package for the Social Sciences, version 20.0. Results: the main indicator for cornea transplant was keratoconus. The mean waiting time for the transplant was approximately 5 months and 3 weeks for elective transplants and 9 days for urgent cases. An association between the type of corneal disorder with gender, age, previous surgery, eye classification, glaucoma and anterior graft failure were found. Conclusion: keratoconus was the main indicator for cornea transplant. Factors such as age, previous corneal graft failure (retransplantation), glaucoma, cases of surgeries prior to cornea transplant (especially cataract surgery) may be related to the onset corneal endothelium disorders.


RESUMEN Objetivo: caracterizar clínicamente los pacientes trasplantados y su distribución, con descripción de las condiciones indicadoras y posoperatorias de los trasplantes de córneas, así como estimar el tiempo promedio en la fila de espera. Método: estudio epidemiológico, transversal, descriptivo y analítico, realizado con todos los trasplantes de córnea realizados en un servicio de referencia (n=258). Los datos fueron analizados con el software Statistical Package for the Social Sciences, versión 20.0. Resultados: la principal condición indicadora para el trasplante de córnea fue el queratocono. El tiempo promedio en fila de espera para realización del trasplante fue de aproximadamente 5 meses y tres semanas, para trasplantes electivos y de 9 días para los casos de urgencia. Existió asociación entre el tipo de disturbio de la córnea con: sexo, intervalo etario, cirugía previa, clasificación del ojo, glaucoma y rechazo del injerto anterior. Conclusión: el queratocono fue la principal condición indicadora para el trasplante de córnea. Factores como: edad; rechazo de injerto de córnea anterior (retrasplante); glaucoma; y casos de cirugías previas al trasplante de córnea, destacando la cirugía de catarata, pueden estar relacionados con el aparecimiento de disturbios de la córnea de tipo endotelial.


RESUMO Objetivo: caracterizar clinicamente os pacientes transplantados e sua distribuição com descrição das condições indicadoras e pós-operatórias dos transplantes de córneas, bem como estimar o tempo médio em fila de espera. Método: estudo epidemiológico, transversal, descritivo e analítico, realizado com todos os transplantes de córnea realizados em um serviço de referência (n= 258). Os dados foram analisados com uso do software Statistical Package for the Social Sciences, versão 20.0. Resultados: a principal condição indicadora para o transplante de córnea foi o ceratocone. O tempo médio em fila de espera para realização do transplante foi de aproximadamente 5 meses e três semanas para o transplantes eletivos e 9 dias para os casos de urgência. Existiu associação entre o tipo de distúrbio da córnea com sexo, faixa etária, cirurgia prévia, classificação do olho, glaucoma e falência do enxerto anterior. Conclusão: o ceratocone foi a principal condição indicadora para o transplante de córnea. Fatores como idade, falência de enxerto corneano anterior (retransplante), glaucoma, casos de cirurgias prévias ao transplante de córnea, com destaque para a cirurgia de catarata, podem estar relacionados com o aparecimento de distúrbios da córnea do tipo endotelial.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Corneal Transplantation , Corneal Diseases/surgery , Corneal Diseases/epidemiology , Referral and Consultation , Cross-Sectional Studies
9.
Clinics ; 70(11): 748-750, Nov. 2015. tab
Article in English | LILACS | ID: lil-766148

ABSTRACT

OBJECTIVES: Viral conjunctivitis is a common, highly contagious disease that is often caused by an adenovirus. The aim of this study was to evaluate the prevalence of adenoviral conjunctivitis by analyzing data from a prospective clinical study of 122 consecutively enrolled patients who were treated at the Clinical Hospital of the State University of Campinas (UNICAMP) after a clinical diagnosis of infectious conjunctivitis between November 2011 and June 2012. METHODS: Polymerase chain reaction was used to evaluate all cases of clinically diagnosed infectious conjunctivitis and based on the laboratory findings, the prevalence of adenoviral infections was determined. The incidence of subepithelial corneal infiltrates was also investigated. RESULTS: Of the 122 patients with acute infectious conjunctivitis included, 72 had positive polymerase chain reaction results for adenoviruses and 17 patients developed subepithelial corneal infiltrates (13.93%). CONCLUSIONS: The polymerase chain reaction revealed that the prevalence of adenoviral conjunctivitis was 59% in all patients who presented with a clinical diagnosis of infectious conjunctivitis from November 2011 to June 2012. The prevalence of adenoviral conjunctivitis in the study population was similar to its prevalence in other regions of the world.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Adenoviridae Infections/epidemiology , Adenoviridae/genetics , Conjunctivitis, Viral/epidemiology , DNA, Viral/analysis , Brazil/epidemiology , Corneal Diseases/epidemiology , Hospitals, University/statistics & numerical data , Polymerase Chain Reaction , Prevalence , Prospective Studies
10.
Arq. bras. oftalmol ; 78(4): 207-211, July-Aug. 2015. tab, ilus
Article in English | LILACS | ID: lil-759266

ABSTRACT

ABSTRACTPurpose:Epidemiological analysis of limbal transplantation surgeries performed in the Ophthalmologic Hospital of Sorocaba.Methods:Retrospective medical records review of 30 patients who underwent limbal stem cell transplants between January 2003 and March 2008. Cases involving conjunctival limbal autograft were classified as group I, and those involving conjunctival limbal allograft as group II.Results:Two patients were excluded due to incomplete data during postoperative follow-up. Of the total sample of 28 patients, 53.6% constituted group I, whereas 46.4% were included in group II. Males were predominant (67.9%), and right eyes were the most prevalent (67.9%). The mean age was 40.3 years. Unilateral cases accounted for 60.7%. The most frequent pathology causing limbal system failure was chemical burns (53%). The mean length of time from diagnosis to surgery was 11.18 years. The limbal graft and amniotic membrane were associated in 75% of all cases, and tarsorrhaphy in 57.1%. The average follow-up period was 24.84 months. The uncorrected visual acuity improved in 38% of the cases, was unchanged in 28.5%, and deteriorated in 33.3%. There was no persistent epithelial defect in 75% of the patients. The conjunctivalization rate was similar between the groups (53.3% and 58.3%, respectively). The transparency improved in only 38.4% of the cases, and 28.5% of the surgeries performed were successful. The most prevalent complication was persistent epithelial defect, which occurred in 25% of the patients, followed by corneal melting in 14.2%. Other complications observed included infectious ulcers, limbal graft necrosis or ischemia, perforation, and descemetocele.Conclusion:Chemical burns remain the main cause of limbal stem cell deficiency. In these cases, limbal transplantation is the standard procedure to restore the ocular surface even though the success rate is low.


RESUMOObjetivo:Análise epidemiológica dos transplantes de limbo realizados no Hospital Oftalmológico de Sorocaba.Método:Foi realizada uma análise retrospectiva através de revisão de prontuário de trinta casos de transplante de limbo realizados no período de janeiro de 2003 a março de 2008. Casos de transplante de limbo autólogo foram classificados como grupo I e alogênicos como grupo II.Resultados:Dois pacientes foram excluídos da análise por insuficiência de dados nos registros. Da amostra completa de 28 pacientes, 53,6% constituíram o grupo I enquanto 46,4% o grupo II. O olho direito (68%) e o sexo masculino (68%) foram mais acometidos, com uma média de idade de 40,3 anos. Casos unilaterais contabilizaram 60,7%. A patologia de base causadora da deficiência límbica mais prevalente foi a queimadura química (53%). A média do tempo de doença até a cirurgia foi de 11,18 anos. Na maioria dos casos o transplante foi associado a membrana amniótica (75%) e tarsorrafia (57%). O tempo médio de seguimento foi de 24,84 meses. Foi observado melhora da acuidade visual não corrigida em 38% dos casos enquanto 28,5% permaneceram inalteradas e 33,3% pioraram. Evolução sem defeito epitelial persistente ocorreu em 75% dos pacientes. A taxa de conjuntivalização foi semelhante nos 2 grupos (53,3% e 58,3%). Em apenas 38% dos casos houve melhora da transparência. A taxa de sucesso foi de cerca de 28%. A complicação mais prevalente foi defeito epitelial persistente (25%) seguida de melting (14,2%). Outras complicações observadas foram úlceras infecciosas, necrose ou isquemia do enxerto, perfuração e descemetocele.Conclusões:A queimadura química permanece como principal patologia causadora de deficiência límbica. Nestes casos o transplante de limbo é atualmente a técnica de eleição para restauração da superfície ocular, porém com baixa taxa de sucesso.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Amnion/transplantation , Conjunctiva/transplantation , Corneal Diseases/surgery , Limbus Corneae/cytology , Stem Cell Transplantation , Brazil/epidemiology , Corneal Diseases/epidemiology , Corneal Diseases/etiology , Postoperative Complications , Retrospective Studies , Treatment Outcome
11.
Article in English | IMSEAR | ID: sea-159349

ABSTRACT

Climatic droplet keratopathy (CDK) is one of the most frequent degenerative corneal diseases with high prevalence rates, especially in equatorial and polar regions. Th e profound hypoesthesia observed in some cases with advanced CDK may contribute to the occurrence of trophic-corneal ulceration, rapid bacterial over infection, diffi culty of healing and relentless evolution to perforation. Superfi cial keratectomy, lamellar or penetrating keratoplasty and excimer laser phototherapeutic keratectomy are various surgical options that have been tried in the management of CDK involving the visual axis, impairing the vision. We attempted conjunctivo-limbal autograft (CLAG) in a patient of advanced CDK with corneal ulceration and studied the outcome at the end of 6 weeks and found a better corneal epithelial regeneration post CLAG.


Subject(s)
Aged , Corneal Diseases/epidemiology , Corneal Diseases/surgery , Corneal Transplantation/methods , Corneal Ulcer/epidemiology , Corneal Ulcer/surgery , Humans , Hypesthesia , Limbus Corneae/surgery , Male , Photorefractive Keratectomy/methods , Tears , Transplantation, Autologous
12.
Rev. bras. oftalmol ; 73(3): 148-153, May-Jun/2014. graf
Article in Portuguese | LILACS | ID: lil-727184

ABSTRACT

Foram examinadas 431 córneas de receptores de transplantes no Rio de Janeiro recebidas em sua maioria do Banco de Olhos associado à Sociedade Brasileira de Oftalmologia (SBO) e, as últimas, do Rio-transplante, após o fechamento temporário do Banco de Olhos. É notável a diferença entre os percentuais e o ordenamento das principais causas de transplante achadas neste levantamento, todos por comprovação histopatológica dos diagnósticos, e as citadas em bibliografia encontradas em Sorocaba, Porto Alegre, Florianópolis, Manaus e Recife baseadas apenas no levantamento dos prontuários clínicos.


Four hundred and thirty one cornea from transplant receptors in Rio de Janeiro were analised, most of them received from Banco de Olhos, associated to Brazilian Society of Ophtalmology (SBO) and from Rio-transplante, after temporary closing of Banco de Olhos. There is a markable difference between the percentual and incidence from the most important causes founded in this work, all of them prooved by histopathology, and the causes reported in bibliography at Sorocaba, Porto Alegre, Florianópolis, Manaus and Recife, based only in clinical archives.


Subject(s)
Humans , Male , Female , Corneal Transplantation/statistics & numerical data , Cornea/pathology , Corneal Diseases/etiology , Corneal Diseases/pathology , Corneal Diseases/epidemiology , Eye Banks/statistics & numerical data , Eye Banks/supply & distribution
13.
Rev. bras. oftalmol ; 73(3): 162-166, May-Jun/2014. tab, graf
Article in Portuguese | LILACS | ID: lil-727180

ABSTRACT

Objetivo: Avaliar o perfil epidemiológico dos pacientes submetidos à ceratoplastia no estado de Santa Catarina e as principais indicações para este procedimento. Métodos: Foi realizado estudo observacional, descritivo e retrospectivo com dados de 1161 pacientes transplantados entre janeiro de 2008 e dezembro de 2010, de acordo com os prontuários obtidos na Central de Notificação, Captação e Distribuição de Órgãos e Tecidos de Santa Catarina. As variáveis registradas foram: idade, sexo, procedência, data do transplante, indicação e olho operado. Resultados: A média de idade foi de 45,51 anos e o sexo masculino foi mais prevalente (54,05%). O ceratocone foi a doença mais frequente (36,09%), seguido por falência do enxerto (15,89%), leucoma (11,92%), ceratopatia bolhosa (11,06%), distrofias (7,77%), úlcera (5,36%), perfuração corneana (5,27%), descemetocele (4,66%), ceratite herpética (1,12%) e ectasia corneana (0,86%). A região do estado com maior número de casos foi a Grande Florianópolis (23,75%), sendo o ceratocone a principal indicação (30,91%). Leucoma e perfuração foram as principais indicações em pacientes com idade inferior a 10 anos, ceratocone nos pacientes entre 11 e 50 anos, falência do enxerto entre 51 e 60 anos e ceratopatia bolhosa nos pacientes acima de 61 anos. Conclusão: O ceratocone é a principal indicação para ceratoplastia no estado de Santa Catarina, com a média de idade de 31 anos. A maioria dos pacientes é do sexo masculino e proveniente da Grande Florianópolis. .


Purpose: To define the epidemiological aspects of the patients submitted to keratoplasty in the state of Santa Catarina, Brazil and the main indications for this procedure. Methods: We conducted an observational, descriptive and retrospective study with the data of 1161 patients submitted to cornea transplantation from january 2008 to december 2010, at the Transplantation Center of Santa Catarina. The analyzed data were: age, gender, origin, transplant date, indication and transplanted eye. Results: The mean age was 45.51 years and men were more commonly operated. Keratoconus was the most common disease (36.09%), followed by graft failure (15.89%), leukoma (11.92%), bullous keratopathy (11.06%), dystrophy (7.77%), ulcer (5.36%), corneal perforation (5.27%), descemetocel (4.66%), herpetic keratitis (1.12%) and corneal ectasia (0.86%). The region with the greater number of cases was the Great Florianopolis (23.75%), with keratoconus as the main indication (30.91%). Leukoma and perforation were the mainly indication in patients under 10 years old, keratoconus in patients between 11 and 50 years old, graft failure between 51 and 60 years old and bullous keratopathy in patients under 61 years old. Conclusion: Keratoconus is the main indication for keratoplasty in our state, with the mean age of 31 years. Most of the patients were men and from the Great Florianopolis. .


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Corneal Transplantation/statistics & numerical data , Corneal Diseases/surgery , Corneal Diseases/epidemiology , Medical Records , Epidemiology, Descriptive , Retrospective Studies
14.
Arq. bras. oftalmol ; 76(5): 288-291, set.-out. 2013. tab
Article in Portuguese | LILACS | ID: lil-690606

ABSTRACT

OBJETIVO: Descrever a taxa de complicações e os tipos de complicações intraoperatórias e pós-operatórias da ceratoplastia endotelial com desnudamento da Descemet (DSEK). MÉTODOS: Revisão retrospectiva de prontuários de pacientes submetidos à DSEK de 2008 a 2010 no Hospital Oftalmológico de Sorocaba. O estudo teve caráter descritivo, com abordagem quantitativa. RESULTADOS: Cento e dezenove olhos de 118 pacientes foram avaliados. Segundo a doença ocular de base, a maior parte dos pacientes eram portadores da distrofia de Fuchs (60 olhos, 50,4%), seguidos dos portadores de ceratopatia bolhosa do pseudofácico com 55 olhos (46,2%). A cirurgia mais comumente realizada foi o transplante endotelial isoladamente (DSEK), realizado em 65 olhos (54,6%), seguida do DSEK associado à facoemulsificação de cristalino (PHACO-DSEK) em 47 olhos (39,5%) e DSEK associado a outras cirurgias (7 olhos, 5,9%). Oito pacientes foram excluídos do trabalho devido informações cirúrgicas insuficientes em prontuário médico. Em relação às complicações cirúrgicas transoperatórias, foram observados casos isolados de bloqueio pupilar, dissecção irregular do botão, implante reverso do botão, "button-holing" e ruptura de cápsula posterior. Entre as complicações precoces, observou-se descolamento de botão em 21,5% dos olhos no grupo do DSEK, 34,0% no grupo PHACO-DSEK e 57,1% no grupo DSEK associado a outras técnicas cirúrgicas. No que se refere às complicações tardias, observou-se "haze" (opacidade) em interface em 16,9%, 8,5% e 14,2% e glaucoma foi observado em 4,6%, 2,1% e 14,2% dos olhos nos grupos DSEK, PHACO-DSEK e DSEK associado a outras técnicas, respectivamente. Falência pós-rejeição foi observada em 15,3% e 12,7% dos grupos DSEK e PHACO-DSEK, respectivamente. CONCLUSÃO: O transplante endotelial de córnea realizado nesta amostra teve uma taxa de complicações considerada alta se comparado aos transplantes penetrantes convencionais. As complicações mais frequentes foram aquelas relacionadas ao descolamento de botão e à falência pós-rejeição.


PURPOSE: To describe the complication rate and type of intraoperative and postoperative complications of Descemet stripping endothelial keratoplasty (DSEK). METHODS: Retrospective medical records review of patients who underwent DSEK between 2008 and 2010 at the Sorocaba Ophthalmological Hospital. The study was descriptive, using a quantitative approach. RESULTS: One hundred nineteen eyes of 118 patients were evaluated. According to the diagnoses, most patients were diagnosed with Fuchs' dystrophy (60 eyes, 50.4%), followed by patients with pseudophakic bullous keratopathy in 55 eyes (46.2%). The most common procedure performed was DSEK alone, performed in 65 eyes (54.6%), followed by the DSEK associated to phacoemulsification (PHACO-DSEK) in 47 eyes (39.5%) and DSEK associated to other surgeries (7 eyes, 5.9%). Eight patients were excluded from the study due to insufficient information in the surgical record. In relation to the intra-operative complications, isolated cases of pupillary block, irregular manual dissection of button, inverted implantation of the button, button-holing and posterior capsule rupture were noticed. Among the documented early postoperative complications, button detachment was observed in 21.5% of the DSEK alone group; 34.0% in PHACO-DSEK group and 57.1% when DSEK was held jointly with other surgical techniques. Regarding to late complications, interface haze was observed in 16.9%, 8.5% and 14.2%, and glaucoma was observed in 4.6%, 2.1% and 14.2% in DSEK, PHACO-DSEK and DSEK associated to other techniques, respectively. Post rejection graft failure was observed in 15.3% and 12.7% of the eyes after DSEK and. PHACO-DSEK, respectively. CONCLUSION: Endothelial corneal transplant accomplished in this sample showed a high rate of complications when compared to the conventional penetrating keratoplasty. The most frequent complications were related to detachment of the button and graft failure.


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Descemet Stripping Endothelial Keratoplasty/adverse effects , Intraoperative Complications/epidemiology , Postoperative Complications/epidemiology , Brazil/epidemiology , Corneal Diseases/epidemiology , Corneal Transplantation/adverse effects , Descemet Membrane , Keratoplasty, Penetrating , Retrospective Studies , Socioeconomic Factors
15.
Arq. bras. oftalmol ; 76(4): 221-225, jul.-ago. 2013. graf, tab
Article in English | LILACS | ID: lil-686557

ABSTRACT

PURPOSE: To examine the prevalence of ocular surface complaints in Brazilian patients with glaucoma or ocular hypertension who used topical intraocular pressure (IOP)-lowering regimens. METHODS: In this multicenter, noninterventional, single-visit study, adults with glaucoma or ocular hypertension treated with an IOP-lowering regimen were administered the 12-item ocular surface disease index (OSDI) questionnaire. Each response was scored on a 5-point scale, with 0 indicating symptom present none of the time and 4 indicating symptom present all of the time. The average of the 12 item responses for each patient was transformed to a scale from 0 to 100, with higher scores representing worse disabilities. OSDI results then were categorized as absence of OSD (scores of 0-12), mild OSD (scores of 13-22), moderate OSD (scores of 23-32), or severe OSD (scores of 33100). RESULTS: The 173 enrolled patients had a mean age of 61.2 years, were women in 65.3% of cases, and had glaucoma in 89.0% of cases and ocular hypertension in 11.0% of cases. OSDI scores for 158 patients using 1 IOP-lowering therapy indicated no OSD in 37.3% of patients (59/158), mild OSD in 20.9% (33/158), moderate OSD in 17.1% (27/158), and severe OSD in 24.7% (39/158). For the 120 patients using 1 IOP-lowering medication and having a known duration of diagnosis of glaucoma or ocular hypertension, mean OSDI scores were numerically higher (worse) for the 39 patients with a diagnosis ≥6 years long (score 25 [± 20], indicating moderate OSD) than for the 81 patients with a diagnosis lasting <6 years (score 22 [± 20], indicating mild OSD); however, no significant differences in OSDI scores by duration of diagnosis were evident in means (P=0.49), distributions (P≥0.26), or correlation (P=0.77). CONCLUSIONS: A large proportion of Brazilian patients treated with 1 IOP-lowering therapy had some ocular surface complaints.


OBJETIVO: Avaliar a prevalência de sintomas decorrentes de doença de superfície ocular (DSO) em pacientes brasileiros com glaucoma ou hipertensão ocular que utilizam tratamento ocular tópico para redução da pressão intraocular (PIO). MÉTODO: Neste estudo multicêntrico, não intervencional de uma única visita, pacientes adultos com glaucoma ou hipertensão ocular em tratamento para redução da pressão intraocular (PIO) responderam aos 12 itens do questionário "índice de doença da superfície ocular" (OSDI). Cada resposta foi pontuada numa escala de 5 pontos, com 0 (zero) indicando a ausência de sintomas e 4 indicando sintomas presentes todo o tempo. A média de respostas dos 12 itens para cada paciente foi transformada numa escala de 0 a 100, com pontuações mais elevadas representando piores deficiências. Os resultados do OSDI foram categorizados como ausência de DSO (pontuação de 0-12), DSO leve (pontuação de 13-22), DSO moderada (pontuação de 23-32) ou DSO grave (pontuação de 33-100). RESULTADOS: Os 173 pacientes incluídos apresentavam idade média de 61,2 anos, 65,3% eram mulheres (65,3%), tinham glaucoma em 89,0% dos casos e hipertensão ocular em 11,0% dos casos. As pontuações do OSDI para os 158 pacientes utilizando uma medicação para redução da PIO indicaram "DSO ausente" em 37,3% dos pacientes (59/158), "DSO leve" em 20,9% (33/158), "DSO moderada" em 17,1% (27/158) e "DSO grave" em 24,7% (39/158). Para os 120 pacientes utilizando medicação redutora da PIO e com duração conhecida do diagnóstico de glaucoma ou hipertensão ocular, a pontuação média do OSDI foi numericamente superior (pior) para 39 pacientes com diagnóstico realizado há mais de 6 anos (pontuação 25 [± 20] indicando DSO moderado) do que para 81 pacientes com o diagnóstico realizado há menos de 6 anos (pontuação 22 [± 20] indicando DSO leve); no entanto, não houve diferença estatisticamente significativa na média da pontuação OSDI na duração do diagnóstico (P=0.49), distribuição (P≥0,26), ou correlação (P=0,77). CONCLUSÃO: Uma grande proporção de pacientes brasileiros tratados com uma medicação para redução da PIO apresenta sintomas decorrentes de doença da superfície ocular (DSO).


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Corneal Diseases/epidemiology , Dry Eye Syndromes/epidemiology , Ocular Hypertension/complications , Benzalkonium Compounds/therapeutic use , Brazil/epidemiology , Corneal Diseases/chemically induced , Glaucoma/complications , Glaucoma/drug therapy , Intraocular Pressure/drug effects , Ocular Hypertension/drug therapy , Prevalence , Preservatives, Pharmaceutical/therapeutic use , Quality of Life , Reference Values , Surveys and Questionnaires
16.
Indian J Ophthalmol ; 2012 Sept-Oct; 60(5): 423-427
Article in English | IMSEAR | ID: sea-144894

ABSTRACT

Corneal diseases represent the second leading cause of blindness in most developing world countries. Worldwide, major investments in public health infrastructure and primary eye care services have built a strong foundation for preventing future corneal blindness. However, there are an estimated 4.9 million bilaterally corneal blind persons worldwide who could potentially have their sight restored through corneal transplantation. Traditionally, barriers to increased corneal transplantation have been daunting, with limited tissue availability and lack of trained corneal surgeons making widespread keratoplasty services cost prohibitive and logistically unfeasible. The ascendancy of cataract surgical rates and more robust eye care infrastructure of several Asian and African countries now provide a solid base from which to dramatically expand corneal transplantation rates. India emerges as a clear global priority as it has the world's largest corneal blind population and strong infrastructural readiness to rapidly scale its keratoplasty numbers. Technological modernization of the eye bank infrastructure must follow suit. Two key factors are the development of professional eye bank managers and the establishment of Hospital Cornea Recovery Programs. Recent adaptation of these modern eye banking models in India have led to corresponding high growth rates in the procurement of transplantable tissues, improved utilization rates, operating efficiency realization, and increased financial sustainability. The widespread adaptation of lamellar keratoplasty techniques also holds promise to improve corneal transplant success rates. The global ophthalmic community is now poised to scale up widespread access to corneal transplantation to meet the needs of the millions who are currently blind.


Subject(s)
Blindness/epidemiology , Blindness/prevention & control , Blindness/surgery , Blindness/therapy , Cataract/therapy , Cataract Extraction/methods , Corneal Diseases/epidemiology , Corneal Diseases/prevention & control , Corneal Diseases/surgery , Corneal Diseases/therapy , Eye Banks/organization & administration , Eye Banks/trends , Eye Banks/statistics & numerical data , Humans , India/epidemiology
17.
Rev. bras. oftalmol ; 70(6): 384-390, nov.-dez. 2011. tab
Article in Portuguese | LILACS | ID: lil-612911

ABSTRACT

OBJETIVO: Descrever o perfil epidemiológico de pacientes na fila de transplante penetrante de córnea no estado do Pará, Brasil. MÉTODOS: Estudo transversal e retrospectivo, com 1261 pacientes, no período de janeiro de 2001 a dezembro de 2009, cadastrados na fila de espera para transplante de córnea na Central de Notificação, Captação e Distribuição de Órgãos (CNCDO) do Pará. Os dados foram coletados por meio de protocolos baseados nas fichas de cadastro de receptor de córnea na CNCDO, adaptados aos objetivos desta pesquisa. RESULTADOS: Em relação à frequência, obteve-se 51 por cento do sexo masculino; 33,9 por cento na faixa etária de 61 a 80 anos; 18,6 por cento inscritos na CNCDO em 2009; 61 por cento com olho direito acometido; 56 por cento permaneceram ativos na fila; 51,7 por cento que aguardaram 1 a 3 anos o transplante e; 85 transplantes realizados em 2009. As principais indicações para transplante de córnea foram ceratopatia bolhosa (28,2 por cento), leucoma (22 por cento) e úlcera corneana (14,8 por cento). CONCLUSÃO: Verificou-se que não houve diferença entre a frequência dos sexos sendo que a maioria encontrava-se na faixa etária de 61 a 80 anos; inscrita na CNCDO no ano de 2009 (ano em que foi realizado o maior número de transplantes); com o olho direito acometido, permaneceram ativos na fila de espera. Entre os pacientes transplantados, atestou-se que o tempo em fila de espera para transplante de córnea foi longo e inadequado. Ademais, as principais indicações para transplante de córnea no estado do Pará foram ceratopatia bolhosa, leucoma e úlcera corneana.


PURPOSE: To describe the epidemiological profile of patients waiting for penetrating keratoplasty in state of Pará, Brazil. METHODS: Transversal and retrospective study, with 1261 patients, in the period of january 2001 until to december 2009, were registered on the waiting list for corneal transplantation in the Central Notification, Captation and Distribution of Organs (CNCDO) of Pará. Registration forms of cornea receiving were used, adapted to the purposes of this research. RESULTS: In relation to frequency, it was obtained 51 percent male; 33.9 percent aged 61 to 80 years; 18.6 percent enrolled in CNPDO in 2009; 61 percent with the right eye affected; 56 percent remained active in the list; 51.7 percent that waited 1 to 3 years the transplant and; 85 transplants performed in 2009. The main indications for corneal transplantation were bullous keratopathy (28.2 percent), scarring (22 percent) and corneal ulcer (14.8 percent). CONCLUSION: There was no difference between the frequency of the sexes, the majority were aged 61 to 80 years, entered into the CNPDO in the year 2009 (the year it was held the largest number of transplants), with the right eye was affected, and who remained active in the waiting list. Among the transplanted patients, it was certified that the time in the waiting list for corneal transplantation was long and inappropriate. Furthermore, the main indications for corneal transplantation in state of Pará were bullous keratopathy, scarring and corneal ulcer.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Waiting Lists , Corneal Transplantation/statistics & numerical data , Keratoplasty, Penetrating/statistics & numerical data , Corneal Diseases/epidemiology , Cross-Sectional Studies , Retrospective Studies , Corneal Diseases/surgery , Corneal Diseases/diagnosis
18.
Arq. bras. oftalmol ; 71(3): 400-404, maio-jun. 2008. tab
Article in Portuguese | LILACS | ID: lil-486119

ABSTRACT

OBJETIVO: Determinar as principais indicações de transplante penetrante de córnea no Departamento de Oftalmologia da Irmandade da Santa Casa de Misericórdia de São Paulo nos pacientes operados no período de janeiro de 1996 a dezembro de 2005 e compará-las com os dados obtidos entre janeiro de 1991 e dezembro de 1995. MÉTODOS: Realizado estudo retrospectivo dos prontuários de pacientes submetidos a transplante penetrante de córnea no período de janeiro de 1996 a dezembro de 2005. Para comparação dos resultados utilizamos o estudo realizado no nosso serviço em 1998. RESULTADOS: Quinhentos e oitenta e sete transplantes penetrantes de córnea foram realizados no período de janeiro de 1996 a dezembro de 2005. A idade média dos pacientes foi de 49,6 anos e variou de 1 a 91 anos. As principais indicações de transplante penetrante de córnea foram ceratite infecciosa (17,9 por cento), trauma (16 por cento), ceratopatia bolhosa do pseudofácico (14,7 por cento), ceratocone (13,1 por cento), reoperação (12,8 por cento) e herpes (6,6 por cento). CONCLUSÃO: Houve aumento nas indicações de transplante penetrante de córnea nos últimos 10 anos nos casos de ceratite infecciosa, trauma, ceratopatia bolhosa do pseudofácico e herpes e diminuição nos de ceratocone e reoperação.


PURPOSE: To identify the indications for penetrating keratoplasty at the Department of Ophthalmology of the Santa Casa of São Paulo from January 1996 to December 2005 and to compare them with those from January 1991 to December 1995. METHODS: Charts of patients who had undergone penetrating keratoplasty from January 1996 to December 2006 were retrospectively reviewed. RESULTS: There were 587 keratoplasties done in this period. The average age of patients was 49.6 ± 21.1 years (range 1 to 91 years). The most common indications were infectious keratitis (17.9 percent), trauma (16 percent), pseudophakic bullous keratopathy (14.7 percent), keratoconus (13.1 percent), regrafts (12.8 percent) and herpetic keratitis (6.6 percent). CONCLUSION: The leading indications for penetrating keratoplasty were infectious keratitis, trauma, bullous keratopathy, herpetic keratitis. There was a decreasing trend in penetrating keratoplasty for keratoconus and regraft during the last 10 years.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child, Preschool , Female , Humans , Infant , Male , Middle Aged , Young Adult , Corneal Diseases/epidemiology , Keratoplasty, Penetrating/trends , Brazil/epidemiology , Corneal Diseases/surgery , Keratoplasty, Penetrating/statistics & numerical data , Retrospective Studies , Reoperation/statistics & numerical data , Young Adult
19.
Article in English | IMSEAR | ID: sea-42761

ABSTRACT

OBJECTIVE: To assess prevalence and causes of corneal blindness in four hospitals in Thailand and to compare the causes between hospitals. MATERIAL AND METHOD: A retrospective chart review of six hundred and sixty four patients records with best-corrected visual acuity not better than 6/60 in at least one eye due to corneal disease in Siriraj, Mettapracharak, Sappasitthiprasong and Banmee Hospitals in a one-year period were reviewed. The collected data included age, sex, laterality, causes of corneal blindness, and prognosis. RESULTS: Seven hundred and sixty nine eyes with corneal blindness and a median age of 55.0 years were reviewed Leading causes of cornea blindness were corneal infection (35.6%), surgical bullous keratopathy (27.8%), and trauma (14.0%). The prevalence at Siriraj Hospital was 1.7% (498/28,728 patients). Most of the treatable cases (84.6%) underwent penetrating keratoplasty procedures and 73% of patients had a chance of recovery. CONCLUSION: Corneal infection and surgical bullous keratopathy were the leading causes of corneal blindness.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Blindness/epidemiology , Child , Child, Preschool , Corneal Diseases/epidemiology , Corneal Opacity/complications , Eye Infections/complications , Female , Hospitals, Public , Humans , Infant , Keratoplasty, Penetrating/adverse effects , Male , Middle Aged , Prevalence , Retrospective Studies , Risk Factors , Thailand/epidemiology
20.
Arch. chil. oftalmol ; 64(1/2): 69-78, 2007. tab, graf
Article in Spanish | LILACS | ID: lil-665141

ABSTRACT

Objetivo: Determinar la prevalencia de ceguera y sus causas, en personas de 50 años o mayores, en la VIII región del Bio-Bio, Chile. Materiales y método: Sesenta conglomerados de 50 personas, fueron elegidas por muestreo sistemático, siendo examinadas 2915 personas (97 por ciento) entre noviembre del 2006 y marzo del 2007. Se completó registro que incluye visión, examen del cristalino y causa de mala visión. La visión se toma con optotipo "E" (tamaños 20/60 y 20/200), con la corrección disponible y/o agujero estenopeico. El estado del cristalino fue elevado con un oftalmoscopio directo. Los planos de las áreas seleccionadas, fueron provistos por el Instituto Nacional de Estadísticas de Chile. Resultados: La prevalencia de ceguera bilateral ajustada a edad y sexo fue de 1.24 por ciento (CI95 por ciento: 0.8-1.8 por ciento). La catarata fue la principal causa de ceguera, siendo la prevalencia de ceguera por catarata de 0.63 por ciento (CI95 por ciento: 0.3-0.9 por ciento), estimando que afecta a unas 2.624 personas en toda la VIII región. Una limitación visual acumulada por catarata, fue detectada en 9.87 por ciento, estimando que afecta a unas 41.361 personas. Conclusiones: La prevalencia de ceguera es similar a las estimaciones realizadas por la OMS. La catarata es la principal causa de ceguera bilateral y de limitación visual siendo una causa tratable.


Objective: To determine the prevalence of blindness and its causes, in people of 50 years or greater, in VIII the region of the Bio-Bio, Chile. Materials and method: Sixty conglomerates of 50 people were chosen by systematic sampling, being examined 2915 people (97 percent) between November of 2006 and March of 2007. Registry is completed and includes vision, examination of the crystalline and causes of bad vision. The vision is taken with "E" chart (size 20/60 and 20/200), with the correction available and/or estenopeico hole. The state of the crystalline was evaluated with oftalmoscopic direct. The planes of the selected zones, were provided by the National Institute of Statistic of Chile. Results: The prevalence of bilateral blindness fit to age and sex was of 1,24 percent (CI95 percent: 0.8-1.8 percent). The cataract was the main cause of blindness, being the prevalence of blindness by cataract of 0,63 percent (CI95 percent: 0.3-0.9 percent), and affects 2,624 people in all VIII the region. An accumulated visual limitation by cataract, was detected in 9.87 percent, considering that it affects 41,361 people. Conclusions: The prevalence of blindness is similar to the estimations made by the WHO. The cataract is the main cause of bilateral blindness and visual limitation being a treatable cause.


Subject(s)
Humans , Male , Female , Middle Aged , Aged, 80 and over , Blindness/epidemiology , Blindness/etiology , Age and Sex Distribution , Cataract/epidemiology , Chile/epidemiology , Data Collection , Corneal Diseases/epidemiology , Refractive Errors/epidemiology , Prevalence , Visual Acuity
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